Ischemic Neuropathy
Ischemic neuropathy is nerve damage caused by reduced blood flow to the nerves, most often in the legs and feet. This change happens to occurs when arteries become blocked or narrowed, usually due to peripheral artery disease (PAD).
-
Ischemic neuropathy is most common in people with advanced PAD, especially those with critical limb ischemia (severe blockage of blood flow).
-
In one study, only 16% of patients with critical limb ischemia had no nerve symptoms. Most had numbness, burning, tingling, or weakness in the affected foot or leg.
-
Neuropathic pain and sensory loss are much more common in severe PAD than in mild cases. People with critical limb ischemia have much higher scores for nerve pain and disability than those with milder PAD.
-
Nerve damage can affect both feeling and movement, but sensory symptoms like numbness and burning are usually more noticeable than weakness.
How common is Ischemic Neuropathy?






Why is it important?
-
Ischemic neuropathy can cause pain, numbness, tingling, burning, and weakness in the legs or feet. These symptoms can make walking and daily activities difficult.
-
Nerve damage may be permanent if blood flow is not restored. In severe cases, it can lead to wounds, ulcers, or even amputation.
-
The presence of nerve symptoms means the blood flow problem is serious and needs medical attention.
-
Treating the underlying blood flow problem can help prevent further nerve damage and improve symptoms.
Key Points
-
Ischemic neuropathy causes nerve symptoms (numbness, burning, tingling, weakness) in the legs or feet.
-
It is a sign of severe PAD and may indicate a higher risk of limb loss.
-
Early recognition and treatment of PAD can help prevent progression to ischemic neuropathy and its complications.

